5).

Conclusions: Only half of critically ill patients’ surrogates participated in CPR discussions. For those who did participate, most reported good understanding www.selleckchem.com/products/ly2835219.html of resuscitation techniques, but less than half recalled the core components of CPR. (C) 2009 Elsevier Inc. All rights reserved.”
“We report on the structural and electronic properties of swift heavy ion (SHI) irradiated pristine TiO2 thin films, deposited by radio frequency

magnetron sputtering on sapphire substrates. The high resolution x-ray diffraction and Raman measurements show a structural phase transition from anatase to admixture of brookite and rutile phases of TiO2 with increasing SHI fluence followed by a significant distortion in the TiO6 octahedra. The modification in the electronic structure stimulated by SHI irradiation has been investigated using x-ray absorption (XAS) experiments at the O K and Ti L-3,L-2 absorption edges. The O K edge spectra clearly indicate the splitting of the pre-edge

spectral features having t(2g) and e(g) symmetry bands due to structural disorder/distortion induced by irradiation. The intensity of the SHI generated components at the O K edge increases monotonically, which can be correlated to the modification in unoccupancies associated with O 2 p orbitals hybridized with Ti 3 d states. The XAS spectra at the Ti L-3,L-2 edge further authenticate that SHI creates Saracatinib chemical structure a controlled structural disorder/distortion in the TiO6 octahedra. (C) 2011 American Institute of Physics. [doi:10.1063/1.3657466]“
“Non-intermingling, adjacent populations of cells define compartment boundaries; such boundaries are often essential for the positioning and the maintenance of tissue-organizers during growth. In the developing wing primordium of Drosophila melanogaster, signaling by the secreted protein Hedgehog (Hh) is required YM155 in vitro for compartment boundary maintenance. However, the precise mechanism of Hh input remains poorly understood. Here, we combine experimental observations of perturbed Hh signaling with computer simulations of cellular behavior, and connect physical properties of cells to their Hh signaling status. We find that experimental disruption of Hh signaling has observable

effects on cell sorting surprisingly far from the compartment boundary, which is in contrast to a previous model that confines Hh influence to the compartment boundary itself. We have recapitulated our experimental observations by simulations of Hh diffusion and transduction coupled to mechanical tension along cell-to-cell contact surfaces. Intriguingly, the best results were obtained under the assumption that Hh signaling cannot alter the overall tension force of the cell, but will merely re-distribute it locally inside the cell, relative to the signaling status of neighboring cells. Our results suggest a scenario in which homotypic interactions of a putative Hh target molecule at the cell surface are converted into a mechanical force.

(J Am

Vet Med Assoc 2013;242:322-334)”
“Polaprezinc, a chelate compound consisting of zinc and L-carnosine, is clinically used as a medicine for gastric ulcers. It has been shown that induction of heat shock protein (HSP) is involved in protective effects of polaprezine against gastric mucosal injury. In the present study, we investigated whether polaprezinc and its components could induce HSP70 and prevent acetaminophen (APAP) toxicity in mouse primary cultured hepatocytes. Hepatocytes were treated with polaprezine, zinc sulfate or L-carnosine at the concentration of 100 mu M for 9 h, and then exposed to 10 mM APAP. Polaprezinc MS275 or zinc sulfate increased cellular HSP70 expression. However, L-carnosine had no influence on it. Pretreatment of the cells with polaprezine or zinc sulfate significantly suppressed cell death as well as cellular lipid peroxidation after APAP treatment. In contrast, pretreatment with polaprezinc did not affect decrease in intracellular glutathione after APAP. Furthermore, treatment with KNK437, an HSP inhibitor, attenuated increase in HSP70 expression induced by polaprezinc, and abolished protective effect of polaprezine on cell death after APAP. These results suggested that polaprezinc, in particular its zinc component, induces HSP70 expression in mouse primary cultured hepatocytes, and inhibits lipid peroxidation

after APAP treatment, resulting in protection against APAP toxicity.”
“Patients with mixed dyslipidemia have a higher Selleck JQ1 risk of atherosclerotic coronary heart disease than patients with isolated elevated LDL-C. Evidence-based guidelines target LDL-C reduction and other lifestyle factors to reduce risk. However, patients with mixed dyslipidemia have a high risk of vascular events, even with statin treatment to optimal LDL-C levels. Available treatments for other modifiable lipid factors,

such as elevated triglycerides and reduced HDL-C, are underutilized PF477736 cost in such patients since there are no large-scale clinical outcomes trials showing incremental benefit, as well as clinician concerns regarding safety with combination treatment. Recent efficacy and safety trials have demonstrated that the combination of fenofibric acid and a statin improves multiple lipid parameters in patients with mixed dyslipidemia without additional safety concerns compared with the individual monotherapies. Ongoing surrogate and event outcomes trials are testing the incremental benefit of such a combination treatment strategy.”
“Objective-To compare the cardiorespiratory effects of IM administration of dexmedetomidine-buprenorphine (DB) and dexmedetomidine-buprenorphine-ketamine (DBK) in dogs with subsequent reversal with atipamezole.

Design-Prospective, randomized crossover study.

Animals-5 healthy dogs.

(C) RSNA, 2011″
“Background/Objective: Active fixation coronary sinus (CS) leads limit dislodgement and represent an attractive

option to the implanter. Although extraction of passive fixation CS leads is a common and frequently uncomplicated procedure, data regarding extraction of chronically implanted active fixation CS leads are limited. Methods: We performed a retrospective cohort study of patients undergoing active fixation CS lead extraction at six centers. Patient and procedural characteristics, indications for extraction, use of extraction sheath (ES) assistance, and outcomes are reported. Results: Between January 2009 and February 2011, 12 patients underwent transvenous see more lead extraction (TLE) of Medtronic StarFix (R) lead (Medtronic Inc., Minneapolis, MN, USA). The cohort was 83% male with mean age 71 +/- 14 years. Average implant duration was 14.2 +/- 5.7 months (2.323.6). All leads but one were removed for infectious indications (67% systemic infection). AZ 628 chemical structure At the time of explant, the fixation lobes were completely retracted in only one of the 12 cases and ES assistance

was required for lead removal in all cases (58% laser, 25% cutting, 25% mechanical, and 25% femoral). The majority of cases required advancement of the sheath into the CS (75.0%) and often into a branch vessel (41.7%). One lead could not be removed transvenously and required surgical lead extraction. There were no major complications. Examination of the leads after extraction frequently revealed significant tissue growth into the fixation lobes. Conclusions: Although TLE of active

fixation CS leads can be a safe procedure in select patients and experienced hands, powered sheaths and aggressive techniques are frequently required for successful removal despite relatively short implant durations. This raises significant concern regarding future check details TLE of active fixation CS leads with longer implant durations. (PACE 2012; 35:641647)”
“To review our Pediatric Endocrinology Division’s experience with differentiated thyroid carcinoma (DTC) we analyzed retrospectively the records of patients with DTC that had been seen between June 1988 and June 2008.

Results: Forty-five patients (median age 13.7 years, 36 female) were diagnosed (papillary: 40, follicular: 5) with DTC presenting as a solitary nodule (n: 25), thyroid nodule with cervical adenopathy (n: 9) and multinodular goiter (n: 11). All underwent total thyroidectomy with resection of suspicious cervical lymph nodes (CLN). DTC was multicentric in 59% and revealed extrathyroidal extension in 44%. Initially, 44% had CLN metastases and 24% distant metastases. All patients underwent thyroid remnant ablation with (131)I and suppressive treatment. Median follow-up was 5.1 years with a disease-free survival rate at 5 years of follow-up of 75%. Eleven percent presented recurrences.

Conclusion: Pediatric DTC has an aggressive behavior at presentation.

A retrospective chart review and analysis of the patients’ data were conducted.

Results: Malignant transformation arising from ovarian MCT accounted for 1.9% of all ovarian MCT (6/321). Three cases were stage IA and the other three were stage IC. Histologically, three of six cases had squamous cell carcinoma (50%), two had a carcinoid tumor (33%), and one had mucinous adenocarcinoma Fer-1 datasheet (17%). All patients underwent comprehensive surgical staging. Two patients received

adjuvant chemotherapy and one received adjuvant chemoradiation. Five of six patients were observed for 16-104 months and no recurrence was detected. One patient with a carcinoid tumor in stage IC died of disease within 34 months following the surgery.

Conclusion: Early detection of malignant transformation arising from MCT is mandatory for treating patients, but in most patients malignancy was detected intraoperatively. Surgical cytoreduction with a complete staging procedure and adjuvant treatment may be reasonable Selleckchem ALK inhibitor for stage IC. Additionally, prognosis is better when the tumor is completely excised and does not extend beyond the capsule.”
“SETTING: Four human immunodeficiency virus (HIV) clinics located at South African tertiary hospitals.

OBJECTIVE: To assess the effectiveness of highly active antiretroviral therapy (HAART) in reducing incident tuberculosis (TB) in HIV-infected

children.

DESIGN: Retrospective cohort.

RESULTS: A total of 1132 children’s records were included in the study. At R428 cell line entry to the cohort,

the median (interquartile range [IQR]) age, CD4%, CD4 count and viral load of all children was respectively 6.3 years (4.1-8.8), 15% (9.0-22.2), 576 cells/mm(3) (287-960) and 160000 copies/ml (54941.5-449683); 75.9% were started on HAART. The male:female ratio was 1:1, and median follow-up time was 1.7 years. In children whose follow-up included both pre-HAART and on-HAART periods, the incidence of clinically diagnosed TB was respectively 21.1 per 100 person-years (py; 95% CI 18.2-24.4) and 6.4/100 py (95% CI 4.8-8.1), and when restricted to confirmed cases, respectively 3.1/100 py (95% CI 2.2-4.2) and 0.8/1.00 py (95% CI 0.5-1.4). Only 23% of all cases of TB were microbiologically confirmed. Multivariate analyses showed that HAART reduced incident TB by approximately 70%, both for confirmed and all TB cases.

CONCLUSIONS: In this high TB burden country, the incidence of diagnosis of TB in HIV-infected children is at least as high as that of adults. HAART reduces incident TB, but further prospective TB preventive and diagnostic studies are urgently needed in children.”
“The aim of our study is to evaluate the feasibility, safety and efficacy of the percutaneous closure of PFO (abnormal communication between the right and left atrium).

Between July 2009 and October 2012 percutaneous closure was performed in 37 patients.

77 (n = 61); and knee flexion, r = 0.74 (n = 58). The HFMSE differentiated patients by SMN2 copy number (P = .0007); bi-level positive airway pressure use, < 8 versus >= 8 hours/day (P < .0001);

ambulatory status (P < .0001); and spinal muscular atrophy type (P < .0001). The HFMSE demonstrates significant associations with established measures of function, strength, and genotype, and discriminates patients based on function, diagnostic category, and bi-level positive airway pressure need. Time of administration averaged 12 minutes. The HFMSE is a valid, time-efficient outcome measure for clinical trials in spinal muscular atrophy types II and III.”
“Purpose: To analyze the dynamics of the shear modulus of the liver to assess the optimal

driving frequency and to determine Torin 2 mouse the diagnostic accuracy of generalized frequency-independent elasticity cutoff values for staging hepatic fibrosis.

Materials selleck chemicals and Methods: This institutional review board-approved prospective study included 16 healthy volunteers and 72 patients with biopsy-proved liver fibrosis. After obtaining written informed consent, imaging was performed at 1.5-T by using a motion-sensitized echo-planar imaging sequence. Wave excitation was performed by an actuator introducing a superposition of four frequencies (25.0, 37.5, 50.0, 62.5 Hz) of shear waves. The elasticity mu value and the structure geometry parameter alpha were calculated by using the two-parameter springpot model. The performance of magnetic resonance (MR) elastography in staging liver fibrosis was assessed with area under the receiver operating characteristic curve (AUROC) analysis and Spearman correlation analysis.

Results: Elasticity increased with stage of fibrosis, with mean values as follows: for volunteers, 2.25 kPa +/- 0.43 (standard

deviation); stage F1, 2.61 kPa +/- 0.43; stage F2, 3.00 kPa +/- 0.63; stage F3, 3.86 kPa +/- 0.61; and stage F4, 5.86 kPa +/- 1.22. Frequency-independent cutoff values derived for fibrosis and AUROC values, respectively, were as follows: stage F1 or higher, 2.84 kPa and 0.9128; stage F2 or higher, 3.18 kPa and 0.9244; stage KU-57788 datasheet F3 or higher, 3.32 kPa and 0.9744; and equivalent to stage F4, 4.21 kPa and 0.9931. The geometry of the tissue (alpha value) did not correlate with fibrosis. Frequencies of 50.0 Hz and 62.5 Hz displayed the highest diagnostic accuracy.

Conclusion: The diagnostic performance of multifrequency MR elastography in determining the degree of hepatic fibrosis increases with stage of fibrosis. Metrics obtained at the higher frequencies provide better diagnostic performance compared with the lower frequencies. Results of the AUROC analysis demonstrate the high accuracy of frequency-independent cutoff values for staging higher grades of hepatic fibrosis.

These results indicated that the late-flowering phenotype in the double mutant

elf3;sel20 as well as in lhy;cca1 was affected by the presence of darkness. The results suggest that CRY2 may play more essential roles in the acceleration of flowering under LL than LDs or SDs.”
“Gallium (Ga) implantation induced self-atom mixing in crystalline and amorphous germanium (Ge) is investigated utilizing isotopically controlled Ge multilayer structures grown by molecular beam epitaxy. The distribution of the Ga ions and the ion-beam induced depth-dependent mixing of the isotope structure Selleckchem NVP-BSK805 was determined by means of secondary ion mass spectrometry. Whereas the distribution of Ga in the crystalline and amorphous Ge is very similar

and accurately Avapritinib reproduced by computer simulations based on binary collision approximation (BCA), the ion-beam induced self-atom mixing is found to depend strongly on the state of the Ge structure. The experiments reveal stronger self-atom mixing in crystalline than in amorphous Ge. Atomistic simulations based on BCA reproduce the experimental results only when unphysically low Ge displacement energies are assumed. Analysis of the self-atom mixing induced by silicon implantation confirms the low displacement energy deduced within the BCA approach. This demonstrates that thermal spike mixing contributes significantly to the overall mixing of the Ge isotope structures. The disparity observed in the ion-beam mixing efficiency of selleckchem crystalline and amorphous Ge indicates different dominant mixing mechanisms. We propose that self-atom mixing in crystalline Ge is mainly controlled by radiation enhanced diffusion during the early stage of mixing before the crystalline structure turns amorphous, whereas in an already amorphous state self-atom mixing is mediated by cooperative

diffusion events. (C) 2011 American Institute of Physics. [doi:10.1063/1.3658259]“
“HLA antibody screening is conducted routinely prior to kidney transplantation, but the comparative prognostic value and cost-effectiveness of different methods are unclear. Pre-transplant sera of 141 patients transplanted between 1998 and 2000 were screened by ELISA and Luminex assays, and antibody specificities of reactive sera determined using bead array techniques. ELISA screening detected donor-specific antibodies (DSA) in 19 patients, who had a higher incidence of impaired graft function (60% vs. 20%, p = 0.04) and antibody-mediated rejection (AMR) within 90 d after transplantation (AMR, 35% vs. 5%, p = 0.02). Luminex screening detected eight additional patients with DSA, among those one with AMR. Six of eight patients with Luminex-only-DSA reported no prior immunizing events. Death-censored graft survival was shorter only in patients with DSA and AMR (median, 1.7 yr instead of between 9.5 and 11.0 yr for patients without DSA or patients with DSA but no AMR, p < 0.001).

“
“The objective of this paper is to investigate the influence of shallow traps on the signals from Al(2)O(3):C,Mg obtained using time-resolved optically stimulated luminescence (TR-OSL) measurements through experiments and numerical simulations. TR-OSL measurements of Al(2)O(3):C,Mg were carried out and the resulting optically stimulated luminescence (OSL) curves were investigated as

a function of the temperature. The numerical simulations were carried out using the rate-equations for a simplified model of Al(2)O(3):C,Mg containing two types of luminescence centers with different luminescence lifetimes and three types of electron PFTα Apoptosis inhibitor traps (a shallow trap, a main dosimetric trap, and a thermally disconnected deep trap). Both experimental results and simulations show that the OSL signals during and between the stimulation pulses are affected

by the presence of shallow traps. However, with an appropriate choice of timing parameters, the influence of shallow traps 4EGI-1 can be reduced by calculating the difference between the signals during and between stimulation pulses. Therefore, TR-OSL can be useful in dosimetry using materials having a large concentration of shallow traps and OSL components with short luminescence lifetimes, for example Al(2)O(3):C,Mg and BeO. Our results also show that the presence of shallow traps has to be taken into account when using the TR-OSL for discrimination between luminescence centers with different luminescence lifetimes, or separation between the OSL from different materials based on their characteristic luminescence lifetimes. The experimental results also show evidence of thermal assistance in the OSL process of Al(2)O(3):C,Mg. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3584791]“
“Background:

Comparative studies on dietary patterns and long-term mortality are sparse.

Objective: The objective was to examine the relations between 10-y mortality and adherence to the World Health Organization dietary guidelines [Healthy Diet Indicator (HDI)], a Mediterranean-like diet, and a carbohydrate-restricted (CR) diet in elderly Swedish men.

Design: Dietary habits were determined by 7-d dietary records in a population-based this website longitudinal study of 924 Swedish men (age: 71 +/- 1 y). The HDI score (-1 to 8 points), the Mediterranean Diet Score (MDS; 0-8 points), and the CR score (2-20 points) were calculated for each participant. Nonadequate reporters of energy intake were identified (n = 413). Mortality was registered during a median follow-up of 10.2 y. Cox proportional hazards regression, with multivariable adjustments, was used to determine the effects of adherence to each dietary pattern.

Results: Two hundred fifteen and 88 subjects died of all-cause and cardiovascular disease, respectively. In all individuals, risk relations to mortality for each SD increment in the scores were observed for only MDS, with an adjusted hazard ratio (HR) of 0.

Neurourol. Urodynam. 32: 998-1003, 2013. (C) 2012 Wiley Periodicals, Inc.”
“The value of anti-mullerian hormone (AMH) as a marker of the ovarian reserve is becoming clear in a range of clinical contexts. This study reports the external validation of a quadratic model-based AMH-age nomogram using a cohort of 15,834 US women. All models previously investigated for the decline in ovarian reserve (i.e. linear, bi-linear, decay curve, power and quadratic models) tended to overestimate AMH by approximately 11% versus the published nomogram, indicating some between-population heterogeneity. Bootstrapping of 1000 datasets

indicated that the quadratic model provided the best Navitoclax supplier fit, confirming the choice of this model in the AMH-age nomogram. This nomogram can therefore be used with confidence for the interpretation of AMH in clinical populations. (C) 2011, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.”
“This study was conducted to evaluate the effects of different preparation methods on the recovery and quantification of ginsenosides in raw Korean ginseng (Panax ginseng C.A. Meyer). Eight major ginsenosides (Rb(1), Rb(2),

Rb(3), Rc, Rd, Re, Rf, and Rg(1)) were analyzed by high performance liquid chromatography (HPLC), after which the recovery and repeatability of the extraction of those ginsenosides using 3 different preparation methods were compared [A. direct extraction (DE) method, hot MeOH extraction/evaporation/direct dissolution; B. solid C188-9 phase extraction (SPE) method, hot MeOH extraction/evaporation/dissolution/C(18) cartridge adsorption/MeOH elution; C. liquid-liquid extraction (LLE) method, hot MeOH extraction/evaporation/dissolution/n-BuOH fractionation]. Use of the DE method resulted in a significantly higher recovery of total ginsenosides than other methods and a relatively clear peak resolution. Use Of the SPE and LLE methods resulted

in clearer peak resolution, but lower ginsenoside recovery than the DE method. The LLE method showed the lowest ginsenoside recovery and repeatability among the 3 methods. Given that the DE method employed only extraction, evaporation, and a dissolution GSK2399872A inhibitor Step (avoiding complicate and time consuming, purification), this technique may be an effective method for the preparation and quantification of ginsenosides from raw Korean ginseng.”
“Aims: To investigate the effects of subject controlled dorsal genital nerve (DGN) electrical stimulation on neurogenic detrusor overactivity (NDO) in subjects at home. Methods: Subjects underwent a 5-day study at home with DGN stimulation. Stimulation was provided with surface electrodes placed either on the dorsal penile shaft in males and on or close to the clitoris in females. The days 1 and 5 were with no stimulation whereas days 2-4 were with stimulation.

Published by Elsevier Aurora Kinase inhibitor Ltd. All rights reserved.”
“Human embryo vitrification is a promising new technology but clinical outcome data is needed to gauge its effectiveness and safety. While pregnancy and live-birth data is available for blastocyst vitrification, such information is lacking for human embryo vitrification at the 6- to 8-cell

stage. The current work presents clinical and obstetric outcomes from the transfer of embryos vitrified on day 3 at the cleavage stage. A total of 270 transfers were performed. The clinical pregnancy and implantation rates for patients under 38 years of age (n = 200) were 45% and 24%, respectively. Corresponding rates in patients 38-42 years old declined to 29% and 13% (n = 70). Embryonic compaction and/or blastulation by the time of transfer were excellent prognostic indicators of a successful pregnancy outcome. Of the 66 deliveries, 12 (18.2%) were twin pregnancies and nine were preterm (13.6%). The mean birthweight for singletons was

3281 +/- 644 g, compared with 2506 +/- 549 g in the twin pregnancies. A total of 78 infants have been born with no major congenital malformations. These data attest to the efficacy and safety of the vitrification technique for cryopreservation of human embryos at the 6- to 8-cell stage. (C) 2010, Reproductive Healthcare Ltd. Published by Elsevier Ltd. see more All rights reserved.”
“The role of acupuncture on the pregnancy rate has not been evaluated in frozen thawed embryo transfer (FET) cycles. buy GANT61 This randomized double-blind study aimed to determine whether acupuncture

performed on the day of FET improves clinical outcomes. On the day of FET, 226 patients were randomly allocated to either real or placebo acupuncture according to a computer-generated randomization list in sealed opaque envelopes. They received a session of real or placebo acupuncture for 25 min on site immediately after FET. The anxiety level and serum cortisol concentration were evaluated before and after real and placebo acupuncture. There were no significant differences in rates of overall pregnancy, clinical pregnancy, ongoing pregnancy, live birth and implantation in the placebo acupuncture group, when compared with the real acupuncture group. The anxiety level and serum cortisol concentration were similar for both groups. Only the placebo acupuncture group had significantly higher ongoing pregnancy (P = 0.022) and implantation rates (P = 0.038) than those who declined to join the study and received no acupuncture. In conclusion, comparable pregnancy and live birth rates of FET treatment were found in patients who had one session of real or placebo acupuncture after FET. (C) 2010, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

In addition, the SAW also facilitates other microfluidic capabilities. For example, capillary waves excited at the free surface of a sessile drop by the SAW underneath it selleck screening library can be exploited for micro/nanoparticle collection and sorting at nodal points or lines at low powers. At higher powers, the large accelerations off the substrate surface as the SAW propagates across drives rapid destabilization of the drop free

surface giving rise to inertial liquid jets that persist over 1-2 cm in length or atomization of the entire drop to produce 1-10 mu m monodispersed aerosol droplets, which can be exploited for ink-jet printing, mass spectrometry interfacing, or pulmonary drug delivery. The atomization of polymer/protein solutions can also be used for the rapid synthesis of 150-200 nm polymer/protein particles

or biodegradable polymeric shells in which proteins, peptides, and other therapeutic molecules are encapsulated within for controlled release drug delivery. The atomization of thin films behind a translating drop containing polymer solutions QNZ molecular weight also gives rise to long-range spatial ordering of regular polymer spots whose size and spacing are dependent on the SAW frequency, thus offering a simple and powerful method for polymer patterning without requiring surface treatment or physical/chemical templating.”
“Folate-mediated one-carbon metabolism (FOCM) is associated with risk for numerous pathological states including birth defects, cancers, and chronic diseases. Although the enzymes that constitute the biological pathways have been well described and their interdependency through the shared use of folate cofactors appreciated, the biological mechanisms underlying disease etiologies remain elusive. The FOCM network is highly sensitive to nutritional status of several B-vitamins and numerous penetrant gene variants that alter network outputs, but current

computational approaches do not fully capture the dynamics and stochastic noise of the system. Combining the stochastic approach with a rule-based Mizoribine nmr representation will help model the intrinsic noise displayed by FOCM, address the limited flexibility of standard simulation methods for coarse-graining the FOCM-associated biochemical processes, and manage the combinatorial complexity emerging from reactions within FOCM that would otherwise be intractable. WIREs Syst Biol Med 2013, 5:343365. doi: 10.1002/wsbm.1209 For further resources related to this article, please visit the WIREs website.”
“Idiopathic Confetti-like leukoderma in a young Indian is illustrated, emphasizing its cardinal clinical features and histopathological findings, and its differential diagnosis is briefly outlined for instant glance.”
“Documentation of inducible myocardial ischaemia, related to the coronary stenosis of interest, is of increasing importance in lesion selection for percutaneous coronary intervention (PCI).