Analysis on travelers with German origin has not shown any signif

Analysis on travelers with German origin has not shown any significant correlation between type of travel and acquired infectious disease; also there was no significant correlation found between the type of travel “visiting friends and relatives” and destination or the risk to acquire a certain infectious disease. Among 48 travelers of African selleck chemicals origin, almost all (47: 98%) traveled to Africa and

acquired infectious diseases which are highly endemic there, such as malaria (5 cases), schistosomiasis (6 cases), and diarrheal diseases (23 cases). The correlation between African origin and these infectious diseases was highly confounded by travel destination. For travelers with other origins, sample size was low and no correlation with any infectious disease was found. Among the very young travelers of age 0 to

4 years, the duration of travel was significantly longer than that for travelers of age 5 to 19 years. This result was caused by the fact that almost half of the parents with children of age 0 to 4 years stayed abroad for visiting friends and relatives. In the age group 0 to 4 years, the risk for diarrhea, especially acute diarrhea, HSP inhibitor was higher than in the age group 5 to 14 years, as shown in other studies.21,22 Among the travelers of age 5 to 9 years, the risk for acquiring schistosomiasis was significantly higher than that for travelers of the other age groups. This result is caused by the fact that more travelers in that age group stayed in Africa, where schistosomiasis is highly endemic in many regions. In this study, the following trends depending on the age of young travelers were found. With decreasing age, there was an increasing duration

of travel, increasing number of travelers visiting friends and relatives abroad, Gefitinib supplier and increasing risk for acquiring acute diarrhea and dermatologic disorders during travel. Furthermore, with increasing age, there was an increasing number of backpackers (as teenagers prefer traveling by backpacking) and increasing risk for acquiring mononucleosis (as teenagers have an elevated risk mainly caused by kissing) abroad. Besides mononucleosis, dengue fever and malaria were the most frequently detected febrile/systemic diseases, whereas the majority of dengue fever cases were imported by young travelers from Asia (especially in age group 10–14 y) and the majority of malaria cases from sub-Saharan Africa with steady pattern of distribution among the age groups.23 Dermatologic disorders were mainly caused by insect bites and cutaneous larva migrans, which are diseases that can be prevented by some simple precaution.24,25 However, the number of causes for dermatologic disorders was large and an elevated risk for travelers <10 years.

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