“
“We report micromagnetic simulations of magnetization dynamics of a vortex state in the free layer of a circular nanopillar excited by the spin transfer torque effect of a perpendicular to the layer (dot) plane spin-polarized electrical current. The magnetization of the reference layer (polarizer) is assumed to be fixed. A new regime of the dynamic magnetization response to the current is reported: vortex expelling from the dot, subsequent in-plane magnetization oscillations in single domain state, and the vortex return

with an opposite core polarization. We analyze conditions (limits of the vortex state as a nano-oscillator) to achieve steady magnetization oscillations corresponding buy 4SC-202 to a gyrotropic motion of the vortex core in terms of the current intensity. These conditions are formulated via the critical currents and vary greatly with the magnetic damping parameter and the cell size used for micromagnetic simulations. The existing LB-100 solubility dmso experiments on the current induced magnetization dynamics in nanopillars and nanocontacts are discussed. (C) 2010 American Institute of Physics. [doi: 10.1063/ 1.3524222]“
“Previous studies of chronic hepatitis C virus (HCV) treatment have demonstrated variations in response among racial and ethnic groups including poorer efficacy rates among African American and Hispanic

patients. The individualized dosing efficacy vs flat dosing to assess optimaL pegylated interferon therapy (IDEAL) trial enrolled 3070 patients from 118 United States centres to compare treatment with peginterferon (PEG-IFN) alfa-2a and ribavirin (RBV) and two doses of PEG-IFN alfa-2b and RBV. This analysis examines treatment response among the major racial and ethnic groups in the trial. Overall, sustained virologic response (SVR) rates were 44% for white, 22% for African American, 38% for Hispanic and 59% for Asian American patients. For patients with undetectable HCV RNA at treatment week 4, the positive predictive value of

SVR was 86% for white, 92% for African American, 83% for Hispanic and 89% for Asian American patients. The positive predictive values of SVR in those with undetectable HCV RNA at treatment week 12 ranged Tanespimycin solubility dmso from 72% to 81%. Multivariate regression analysis using baseline characteristics demonstrated that treatment regimen was not a predictor of SVR. Despite wide-ranging SVR rates among the different racial and ethnic groups, white and Hispanic patients had similar SVR rates. In all groups, treatment response was largely determined by antiviral activity in the first 12 weeks of treatment. Therefore, decisions regarding HCV treatment should consider the predictive value of the early on-treatment response, not just baseline characteristics, such as race and ethnicity.”
“After our study of a self-management intervention for epilepsy [1], we gathered data on Internet use and computer availability to assess the feasibility of computer-based interventions in a veteran population.