Options vary depending on a woman’s overall health and response to treatment. They include stepped-up acute treatment, mini-prevention with NSAIDs, magnesium, triptans or estrogen,

or daily prevention with continuous contraception. To find more resources, please visit the American Migraine Foundation (http://kaywa.me/ir2eb) “
“(Headache 2010;50:133-137) Objectives.— This study assessed cardiovascular reactivity to mental stress and cold pressure test in migraineurs and controls. It compared the cardiovascular reactivity between patients with migraine with aura and patients with migraine without aura. Background.— Several studies have assessed the autonomic nervous system functioning and cardiovascular responses to stressor stimuli in migraine. Cold Selleck Trichostatin A pressure test and sustained attention tasks are distinct forms of induced stress. It is still unknown if patients with migraine have distinct patterns of response to sustained attention tasks and cold pressure test, since no previous studies have evaluated the cardiovascular responses to these 2 distinct types of stress in the same population of migraine patients. Methods.— Two distinct protocols

were used to induce cardiovascular reactivity. Mental stress was induced by using a Stroop test card, a procedure involving the maintenance of the attention control. The other protocol was the cold pressure test. The blood pressure and Temsirolimus heart rate were digitally recorded in rest and test phases. The mean elevation and the variance of blood pressure and heart rate were compared between groups. Results.— Patients with migraine had higher rest systolic blood pressure and lower heart rate induced by mental stress than controls. There were no differences between migraineurs and controls with cold pressure test. There were no differences between migraineurs with and without aura. Conclusion.— There was a significantly different

pattern of cardiovascular reactivity between migraineurs and controls with mental stress but not with cold pressure test. Distinct central nervous system structures are involved not in these 2 types of stress. A distinct pattern of activation of the prefrontal cortex—periaqueductal gray matter circuit in migraine may explain a singular autonomic reactivity to mental stress in this disease. “
“While the “triptans”—eg, sumatriptan (Imitrex), rizatriptan (Maxalt), eletriptan (Relpax)—have received more promotion and attention over the 2 decades since they first became available for general use, the non-steroidal anti-inflammatory drugs (NSAIDs) long have been a mainstay of treatment for acute migraine headache.