From January 2006 to December 2011, 93 patients (68
PD-1/PD-L1 Inhibitor 3 clinical trial female) with a median age of 46 years underwent laparoscopic SG at our department. Thirteen patients had a history of gastric banding with insufficient weight loss or band-related complications. Clinical outcome and laboratory findings were analyzed.
The mean preoperative and postoperative body mass index (BMI) was 44.1 +/- 6.9 and 33.4 +/- 6.8 kg/m(2), respectively (p < 0.001). The mean excessive body weight loss after a median follow-up of 11.9 months was 55.7 % +/- 24.9 %. Three bleedings, two staple line leakages, and a deep wound infection required conversion to laparotomy (n = 1), reoperation (n = 4), or endoscopic stent implantation (n = 2). Resolution of diabetes and dyslipidemia was seen
in 85 and 50 % of patients, respectively. Blood test Rabusertib in vitro results of HbA1c, cholesterols, triglycerides, and leptin showed significant postoperative improvement.
Laparoscopic SG represents a feasible bariatric procedure with good short-term weight loss, low morbidity rate, and efficient resolution of diabetes and dyslipidemia, especially in patients with lower BMI. The significant decrease of leptin necessitates further studies to understand the ambiguous role of leptin in bariatric surgery.”
“The objective of this study was to evaluate 2 years post-surgical loss of three-dimensional correction in adolescent idiopathic scoliosis (AIS) patients using multi-planar reconstruction computed tomography (CT).
Twenty-seven AIS patients treated by segmental pedicle screw (PS) constructs were included in this study. Correction in the axial plane was evaluated using the “”relative apical vertebral rotation angle”" (rAVR), defined as the difference between the axial rotation angles of the upper instrumented vertebra and the apical vertebra on reconstructed axial CT images. The Cobb angle of the main curve and apical vertebral
translation was measured to evaluate the coronal correction. Epigenetics inhibitor Thoracic kyphosis was also measured for the evaluation of sagittal profile. Measurements were performed before surgery, and 1 week and 2 years after surgery. The relationships between the correction losses and skeletal maturity, and variety of spinal constructs were also evaluated.
The mean preoperative Cobb angle of the major curve was 59.1A degrees A A +/- A 11.2A degrees before and 13.0A degrees A A +/- A 7.2A degrees immediately after surgery. Two years later, the mean Cobb angle had increased significantly, to 15.5A degrees A A +/- A 7.8A degrees, with a mean correction loss of 2.5A degrees A A +/- A 1.5A degrees (p < 0.001). The mean preoperative rAVR of 28.5A degrees A A +/- A 8.4A degrees was corrected to 15.8A degrees A A +/- A 7.8A degrees after surgery. It had increased significantly to 18.5 +/- A 8.4 by 2 years after surgery, with a mean correction loss of 2.7A degrees A A +/- A 1.0A degrees (p < 0.001).