: Complicated intra-abdominal infections in BYL719 ic50 Europe: a comprehensive review of the CIAO study. World J Emerg Surg 2012,7(1):36.PubMedCrossRef Competing interests The authors declare that they have no competing interests. Authors’ contributions MS designed the study and wrote the manuscript. All authors AZD5153 read and approved the final manuscript.”
“Article Introduction Thoracic wall (TW) reconstruction involves different surgical specialties as oncologic, plastic or trauma surgeon. Despite progress in reconstructive techniques,

rebuilding portions of the thorax remains challenging, in particular when large resections, contamination or infection are involved. The successful reconstruction must preserve thoracic wall stability and respiratory function, eliminate dead spaces, avoid or reduce the risk of infection and protect the underlying viscera [1, 2]. Indications for full thickness resection of thoracic wall are primary thoracic tumors, extensive extra-thoracic neoplastic diseases, congenital aplasia or traumatic events [3–5]. Beyond anatomical repair with soft tissue flaps and plastic surgery techniques many different prosthetic materials have been used for TW reconstruction. Polypropylene, polyester, expanded polytetrafluoroethylene

(PTFE) and polyethylmethacrylate sandwiched between layers of polypropylene have been used [6]. In the last 15 years innovative materials QNZ manufacturer have been introduced. Biological meshes comprised of several different materials: partially remodeling prosthesis are made of porcine dermal collagen Florfenicol (PDC), human dermal collagen (HDC), and bovine pericardium collagen (BPC). Completely remodeling prostheses are made of swine intestinal sub-mucosa (SIS), HDC and BDC. The partially remodeling prostheses are optimal in TW or abdominal reconstruction because of they resist better to mechanical stress. They are physically modified with cross-linkages between the collagen fibers

which strengthen them [7, 8]. In trauma surgery it often happens to stabilize thoracic wall injuries. Different techniques have been reported with different devices. The main challenge in trauma surgery is the potential contamination or the infection of the surgical field. One of the main characteristic of biological materials is the possibility to be used safely in contaminated or infected fields. Biological prostheses have already demonstrated their usefulness and versatility in many fields [9–15]. However as the main part of literature is composed by case series and case reports, they still require more evidence-based data [16]. Recently a decisional model about the use of these mesh have been proposed by the Italian Biological Prosthesis Work Group [17]. In the last years the Italian Chapter of the European Hernia Society started the Italian Register of Biological Prosthesis (IRBP).