Biochem Biophys Res Commun 2004,325(2):612–618.buy CUDC-907 PubMedCrossRef 32. Lopez B, Aguilar D, Orozco H, Burger M, Espitia C, Ritacco V, Barrera L, Kremer K, Hernandez-Pando R, Huygen K, et al.: A marked difference in pathogenesis and immune response induced

by different Mycobacterium tuberculosis genotypes. Clin Exp Immunol 2003,133(1):30–37.PubMedCrossRef 33. Mawuenyega KG, Forst CV, Dobos KM, Belisle JT, Chen J, Bradbury EM, Bradbury AR, Chen X: Mycobacterium tuberculosis functional network analysis by global subcellular protein profiling. Mol Biol Cell 2005,16(1):396–404.PubMedCrossRef 34. Jucker M, Tian M, Norton DD, Sherman C, Kusiak JW: Laminin alpha 2 is a component of brain capillary basement membrane: reduced expression in dystrophic dy mice. Neuroscience 1996,71(4):1153–1161.PubMedCrossRef Akt inhibitor 35. Powell SK, Evofosfamide molecular weight Kleinman HK: Neuronal laminins and their cellular receptors. Int J Biochem Cell Biol 1997,29(3):401–414.PubMedCrossRef 36. Av-Gay Y, Everett M: The eukaryotic-like Ser/Thr protein kinases of Mycobacterium tuberculosis. Trends Microbiol 2000,8(5):238–244.PubMedCrossRef 37. Prisic S, Dankwa S, Schwartz D, Chou MF, Locasale JW, Kang CM, Bemis G, Church GM, Steen H, Husson RN: Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases. Proc Natl

Acad Sci USA 107(16):7521–7526. 38. Perez J, Garcia R, Bach H, de Waard JH, Jacobs WR Jr, Av-Gay Y, Bubis J, Takiff HE: Mycobacterium tuberculosis transporter MmpL7 is a potential substrate for kinase PknD. Biochem Biophys Res Commun 2006,348(1):6–12.PubMedCrossRef 39. Greenstein AE, MacGurn JA, Baer CE, Falick AM, Cox JS, Alber T: M. tuberculosis Ser/Thr Protein Kinase D Phosphorylates an Anti-Anti-Sigma Factor Homolog. PLoS Pathogen 2007,3(4):e49.CrossRef 40. DeMaio J, Zhang Y, Ko C, Young DB, Bishai WR: A stationary-phase stress-response sigma factor from Mycobacterium tuberculosis. Proc Natl Acad Sci USA 1996,93(7):2790–2794.PubMedCrossRef Docetaxel 41. Geiman DE, Kaushal D, Ko C, Tyagi S, Manabe

YC, Schroeder BG, Fleischmann RD, Morrison NE, Converse PJ, Chen P, et al.: Attenuation of late-stage disease in mice infected by the Mycobacterium tuberculosis mutant lacking the SigF alternate sigma factor and identification of SigF-dependent genes by microarray analysis. Infect Immun 2004,72(3):1733–1745.PubMedCrossRef 42. Jain SK, Paul-Satyaseela M, Lamichhane G, Kim KS, Bishai WR: Mycobacterium tuberculosis invasion and traversal across an in vitro human blood-brain barrier as a pathogenic mechanism for central nervous system tuberculosis. J Infect Dis 2006,193(9):1287–1295.PubMedCrossRef 43. Barthe P, Mukamolova GV, Roumestand C, Cohen-Gonsaud M: The structure of PknB extracellular PASTA domain from mycobacterium tuberculosis suggests a ligand-dependent kinase activation. Structure 2010,18(5):606–615.PubMedCrossRef 44.