1). Table 2 Commercial imports of live captive-bred CITES Appendix II-listed poison arrow frogs in 1987–2008 with Kazakhstan as reported origin, highlighting the role of CH5183284 chemical structure Thailand as an importer and re-exporter and showing exports were restricted to the years 2004 and 2005 (Lebanon is not party to CITES) Species Trade 1987–2003 2004 2005 2006 2007 2008 Exporter Importer Dendrobates

amazonicus Export 0 20 0 0 0 0 Lebanon Thailand Dendrobates auratus Export 0 100 100 0 0 0 Lebanon Thailand Re-export     10 20 0 0 Thailand Taiwan Dendrobates azureus Export 0 240 200 0 0 0 Lebanon Thailand         5 0 Thailand S Korea Dendrobates fantasticus Export 0 30 30 0 0 0 Lebanon Thailand Dendrobates galactonotus Export 0 100 100 0 0 0 Lebanon Thailand Re-export     30 7 0 0 Thailand Taiwan Dendrobates imitator Export 0 0 50 0 click here 0 0 Lebanon Thailand PSI-7977 ic50 Dendrobates lamasi Export 0 40 40 0 0 0 Lebanon Thailand Dendrobates leucomelas Export 0 100 100 0 0 0 Lebanon Thailand Dendrobates pumilio Export 0 100 100 0 0 0 Lebanon Thailand Dendrobates reticulatus Export 0 100 100 0 0 0 Lebanon Thailand Dendrobates tinctorius Export 0 200 200 0 0 0 Lebanon Thailand Re-export     18 20 0 0 Thailand Taiwan Re-export       6 0 0 Thailand Philippines         30 0 Thailand S Korea Dendrobates ventrimaculatus Export 0 20 40 0 0 0 Lebanon Thailand

Dendrobates spp Re-export 0 50 0 0 0 0 Lebanon Thailand Phyllobates bicolor Export 0 100 100 0 0 0 Lebanon Thailand         10 0 Thailand S Korea Phyllobates terribilis Export 0 100 100 0 0 0 Lebanon Thailand Epipedobates tricolor Export 0 50 50 0 0 0 Lebanon Thailand Re-export       5 0 0 Thailand South Korea Cryptophyllobates azureiventris Export 0 0 40 0 0 0 Lebanon Thailand Fig. 1 Trade routes of dendrobatid frogs from Kazakhstan and Lebanon Rolziracetam to Thailand and thence to South Korea, Taiwan Province of China and the Philippines. Size of arrows are proportional (log10-transformed) to the volumes traded. The dotted line indicates a minimum number of individuals

following an assumed route from range States Discussion This analysis shows high levels of international trade in dendrobatid frogs, six times higher than reported by Gorzula (1996) more than a decade ago. Compared to the late 1980s–early 1990s (Gorzula 1996), 12 species were no longer reported to be in international trade whereas 18 new ones appeared in recent years. There are large differences between numbers of captive-bred versus wild-caught dendrobatid frogs. Gorzula (1996) reported 14% of the total international trade to be captive-bred, whereas currently 91% of the individuals are reported as such (with an additional 5% comprising ranched or F1 captive-born individuals).