05 1.11 1.01–1.21 Atopic eczema (past or current) 18.30 1.16 1.05–1.28 Age group  ≤ 32 25.95 1.00 (reference)  33–46 23.19 1.48 1.32–1.66  47–60 25.25 1.81 1.62–2.03  ≥ 61 25.60 1.87 1.63–2.14 Study period  1992–1996 31.62 1.00 (reference)  1997–2001 34.17 0.81 0.74–0.89

 2002–2006 34.22 0.77 0.70–0.85 Anatomical site  Trunk 3.61 1.00 (reference)  Axillae 0.78 0.43 0.15–0.99  Arm(s) 3.83 1.55 1.11–2.19  Hand(s) 29.04 3.15 2.41–4.21  Anogenital 2.56 0.62 0.36–1.02  Leg(s) 10.53 1.54 1.16–2.09  Foot/feet 3.49 PF299 in vitro 1.53 1.09–2.17  Neck 1.32 0.84 0.47–1.42  Face 15.73 1.02 0.76–1.39  Scalp 3.00 0.69 0.43–1.07  Flexures 0.51 1.21 0.53–2.41  Generalised 8.40 1.23 0.90–1.70  “Other” site 8.66 0.71 0.50–1.01 Number of additional contact allergies  None 54.38 1.00 (reference)  1 23.84 2.28 2.05–2.53 Crenigacestat manufacturer  2 11.87 3.60 3.22–4.02  3 5.56 4.39 3.85–5.01  4 or more 4.34 6.98 6.17–7.89 Risk quantified with the prevalence ratio (PR), accompanied by a 95% confidence interval (CI)–first part: non-occupational factors Table 3 Results of a Poisson regression

analysis of 121,051 patients’ data, collected between 1992–2006 by the IVDK network Occupation/occupational group % PR 95% CI Office occupations and teachers 15.66 1.00 (reference) Rubber industry workers 0.07 5.09 2.00–10.48 Physicians and dentists 1.60 3.82 3.02–4.8 Meat and fish processors 0.37 3.48 2.16–5.31 Cleaners 1.99 3.09 2.48–3.84 Nursing occupations 4.58 2.96 2.47–3.56 Florists, forestry workers 0.82 2.74 1.94–3.77 Construction and ceramic workers 1.50 2.68 2.05–3.48 Textile workers 0.75 2.49 1.70–3.52 Geriatric nurses 0.80 2.27 1.61–3.12 Cooks, food preparers Sclareol 1.22 2.21 1.60–2.97 Medical auxiliary personnel 1.04 2.09 1.45–2.94 Farmers, animal keepers 0.68 2.07 1.33–3.06 Old age pensioners, students 33.48 1.82 1.55–2.13 Chemical industry and photo lab workers 0.83 1.55 0.95–2.39 Sales and related service workers 5.20 1.47 1.18–1.83 Miners 0.32 1.44 0.65–2.73 Plastic material workers 0.65 1.42 0.82–2.29 buy Duvelisib Hairdressers, cosmetologists 1.75 1.37 0.99–1.85 Household and guest service workers 11.74 1.34 1.11–1.61

Technicians 3.06 1.25 0.92–1.68 Metal workers 5.17 1.21 0.95–1.53 Bakers and confectioners 0.66 1.18 0.64–1.99 Masseurs 0.49 1.17 0.62–2.00 Paper and printing industry workers 0.44 1.03 0.46–1.94 Painters, carpenters 1.60 1.00 0.64–1.50 Risk quantified with the prevalence ratio (PR), accompanied by a 95% confidence interval (CI)–second part: occupational factors Many occupations and occupational groups, respectively, were associated with a significantly increased risk of contact allergy to the thiuram mix.