“
“Study Design. Cross-sectional design.
Objective. To compare lumbar multifidus electromyographic activity (EMG) during predictable and
unpredictable trunk loading between people with and without recurrent unilateral low back pain (LBP) during symptom remission.
Summary of Background Data. Unpredictable loading is a common injury mechanism for LBP. Paraspinal muscle responses to trunk loading differ between people with and without a history of LBP, but whether the response differs between specific regions within the paraspinal muscles is unclear. Differences between deep (DM) and superficial fibers (SM) of multifidus have been implicated in other tasks. It is unknown whether DM and SM EMG differ between people in remission from recurrent LBP and healthy people during trunk loading.
Methods. DM and SM EMG was recorded bilaterally at L5 with intramuscular electrodes during predictable and unpredictable trunk see more loading and compared Epacadostat research buy during 10 milliseconds epochs (250 milliseconds before to 150 milliseconds after loading) between sides, loading conditions, and groups.
Results. DM EMG increased
above baseline before and after predictable load onset, but returned to baseline at the time of impact. Both DM EMG bursts were less in the remission group and less on the non-painful side. Peak SM EMG amplitude on the previously painful side was earlier in the remission group than healthy participants. DM and SM EMG were less after unpredictable load onset in the remission group than healthy participants.
Conclusion. Despite symptom remission,
DM EMG during predictable loading and DM and SM EMG during unpredictable loading were less in people with recurrent LBP than healthy participants.”
“Background: Recently, it has become increasingly recognized that pulmonary hypertension (PH) is a particularly ominous consequence of left-sided heart failure (HF). The primary aim of this investigation was to assess the ability of key cardiopulmonary exercise testing (CPX) variables to detect elevated pulmonary pressures in a HF cohort.
Methods: This was a retrospective analysis of a prospectively collected database. Two hundred ninety-three subjects with HF (63 +/- 10 years old, 79% male) underwent Doppler echocardiography selleck compound to estimate resting pulmonary artery systolic pressure (PASP). Peak oxygen consumption (VO2), the minute ventilation/carbon dioxide production (VE/VCO2) slope, peak partial pressure of end-tidal CO2 (PETCO2) and exercise oscillatory ventilation (EOV) were determined.
Results: Forty-six percent (n = 134) of the subjects presented with a PASP >= 40 mm Hg. A VE/VCO2 slope </>= 36.0 was the best predictor of a PASP >= 40 mm Hg (odds ratio [OR] 12.1, 95% confidence interval [CI] 6.8-21.4; P < .001). Peak PETCO2 <= 34 mm Hg (OR 3.8, 95% CI 1.3-11.2; P < .001) and the presence of EOV (OR 3.2, 95% CI 1.8-5.8; P < .